A new-type HOCl-activatable fluorescent probe and its applications in water environment and biosystems새로운 유형의 HOCl 활성화 가능한 형광 프로브 및 물 환경 및 생물 시스템에서의 응용Article Published on 2022-09-152022-09-11 Journal: The Science of the total environment [Category] 치료기술, 치료제, [키워드] Accuracy Affect aggregate assistance Biotin biotinylated Cancer cancer cell Cancer cells cancer diagnosis Cell cells chlorine Concentration Consumption contribute convenience Corona COVID-19 Early Cancer expected Fluorescence fluorescent Fluorescent probe Health HOCl human body hypochlorite hypochlorous acid inflammatory disease Inflammatory diseases introduced kill membrane outbreak overexpressed oxygen PBS Precision probe reactive oxygen specy receptor ROS significant increase sodium sodium hypochlorite Spread Virus Disease viruses water Water samples. while [DOI] 10.1016/j.scitotenv.2022.156164 PMC 바로가기 [Article Type] Article
Prospective two-arm study of the testicular function in patients with COVID-19COVID-19 환자의 고환 기능에 대한 전향적 양군 연구Clinical Trial Published on 2022-09-012022-09-11 Journal: Andrology [Category] COVID19(2023년), SARS, 임상, 치료기술, [키워드] Affect Agglutination reaction Analysis Autopsies Autopsy Cell Chest computed tomography collected Community Computed tomography Control COVID-19 COVID-19 pandemic COVID-19 patient damage died Direct discharge discharge home disorder Effect exhibited follicle-stimulating hormone Health Organization healthy control healthy controls Hospital stay human body increase in infiltration Inflammation International Laboratory lack Luteinizing Hormone majority male male fertility male hormone male reproductive system management MAR material moderate moderate to severe multiple organ multiple organs parameter participant Patient patients with COVID-19 patients with moderate positive postmortem examination Prospective Prospective Study reproductive reproductive system Research returned SARS-CoV-2 Semen Semen analysis severe disease significantly Sperm spermatogenesis Symptom testes testes. testicle Testosterone the disease the healthy throat swab tissue Topic Trial Two-arm Viral pneumonia virus was performed WHO World Health Organization [DOI] 10.1111/andr.13159 PMC 바로가기 [Article Type] Clinical Trial
SARS-CoV-2-positive patients display considerable differences in proteome diversity in urine, nasopharyngeal, gargle solution and bronchoalveolar lavage fluid samplesSARS-CoV-2-양성 환자는 소변, 비인두, 양치액 및 기관지폐포 세척액 샘플에서 단백질체 다양성에 상당한 차이를 나타냅니다.Article Published on 2022-08-082022-09-11 Journal: PLoS ONE [Category] SARS, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 BALF Beijing Bronchoalveolar lavage fluid center chance change characterized Charle China collected coronavirus coronavirus 2 database demonstrated Department downloaded followed by gargle gargle solution Germany Human human body in urine individual infected with SARS-CoV-2 Infection information investigated Mayo Clinic Medicine nasopharyngeal nasopharyngeal sample Nasopharyngeal samples pathology peptide Protein Proteins proteome proteomic proteomics respiratory SARS-CoV-2 SARS-CoV-2 pathogenesis SARS-CoV-2 protein SARS-CoV-2 proteins SARS-CoV-2 proteome SARS-CoV-2 virus SARS-CoV-2 viruses SARS-CoV-2-positive patient SARS-CoV-2-positive patients Science secreted seropositive individuals Severe acute respiratory syndrome significantly more solution status technology the SARS-CoV-2 virus UniProt unique university Urine USA virus viruses was used while [DOI] 10.1371/journal.pone.0271870 PMC 바로가기 [Article Type] Article
CLEVER assay: A visual and rapid RNA extraction-free detection of SARS-CoV-2 based on CRISPR-Cas integrated RT-LAMP technologyCLEVER 분석: CRISPR-Cas 통합 RT-LAMP 기술을 기반으로 하는 SARS-CoV-2의 시각적이고 신속한 RNA 추출 없는 검출Article Published on 2022-08-012022-09-11 Journal: Journal of Applied Microbiology [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 clinical sensitivity clustered regularly interspaced short palindromic repeats coronavirus COVID-19 COVID-19 diagnosis COVID-19 outbreak COVID-19 pandemic CRISPR CRISPR-Ca CRISPR-Cas12 develop diagnose Diagnosis epidemiological equipment extraction-free method faster guide RNA hospital human body infected patients integration Internal control involved Isolation isothermal amplification lab LAMP lateral flow lateral flow readout. limit logistics Loop-mediated isothermal amplification major defect management nasopharyngeal offer Oropharyngeal overcome Palindromic point-of-care POP7 Region Repeat reverse transcription RNA RNA extraction RNA isolation RNase P RT-LAMP SARS-CoV-2 SARS-CoV-2 detection severe acute respiratory syndrome Coronavirus Significance specificity stick the patient urgency Visual with COVID-19 [DOI] 10.1111/jam.15571 PMC 바로가기 [Article Type] Article
Neuropilin (NRPs) Related Pathological Conditions and Their Modulators뉴로필린(NRP) 관련 병리학적 상태 및 조절인자Review Published on 2022-07-292022-09-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 addition Analysis antagonists Cancer clinical disease Community computer-aided drug design condition COVID-19 COVID-19 research Diversity foci form homologous human body in silico in silico drug design joint Last Ligand ligands modulator neuropathic neuropathic pain neuropilin neuropilins NRP1 Pain pathological pathological conditions pathological role peptidomimetics physiological receptor receptor modulator design small molecule small-molecule antagonists. splice the SARS-CoV-2 therapeutic tissue transmembrane glycoprotein variant variety vertebrates viral entry [DOI] 10.3390/ijms23158402 PMC 바로가기 [Article Type] Review
Promising Strategies for Preserving Adult Endothelium Health and Reversing Its Dysfunction: From Liquid Biopsy to New Omics Technologies and Noninvasive Circulating Biomarkers성인 내피의 건강을 유지하고 그 기능 장애를 되돌리기 위한 유망한 전략: 액체 생검에서 새로운 Omics 기술 및 비침습적 순환 바이오마커까지Review Published on 2022-07-072022-09-11 Journal: International Journal of Molecular Sciences [Category] MERS, 바이오마커, 진단, [키워드] acute respiratory distress acute respiratory distress syndrome Biomarker Biomarkers biomarkers and therapeutic targets biopsy cardiovascular system Clinical studies condition COVID-19 disease distress dysfunction endothelial Endothelial dysfunction Endothelium endothelium dysfunction Evidence functions human body Inflammation liquid network medicine New newer omics technologies. nutrition omics technologies oxygen Pathogenesis Potential biomarker potential biomarkers Preserving respiratory distress resulting Sepsis Strategy syndrome technology therapeutic therapeutic target therapeutic targets tissue tissues vascular homeostasis [DOI] 10.3390/ijms23147548 PMC 바로가기 [Article Type] Review
[Optimal oxygen administration-new evidence from treating COVID-19?][최적의 산소투여-코로나19 치료의 새로운 증거?]Review Published on 2022-06-012022-09-11 Journal: Medizinische Klinik, Intensivmedizin Und Notfallme [Category] 치료제, [키워드] activate Cell cells changes in Clinical practice compensatory mechanism compensatory mechanisms coronavirus disease Coronavirus disease 2019 COVID-19 disorders English environmental factors Evidence functional Gang highlight human body human cells hypoxia Injury integrity invasive knowledge Lactates mechanism organ damage organ systems oxygen Oxygen consumption oxygen levels oxygen saturation Oxygenation pandemic pathophysiology physiological mechanism Physiology Physiology. Prevent remain unchanged risk Side effect survival target therapeutic strategy therapy [DOI] 10.1007/s00063-022-00914-8 PMC 바로가기 [Article Type] Review
Sonic hedgehog pathway for the treatment of inflammatory diseases: implications and opportunities for future research염증성 질환 치료를 위한 음파 고슴도치 경로: 향후 연구를 위한 의미 및 기회Editorial Published on 2022-06-012022-09-11 Journal: Journal for immunotherapy of cancer [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Activation acute myeloid leukemia Airway inflammation allergy Arthritis Asthma atopic dermatitis Autoimmune diseases Basal cell basal cell carcinoma Breast cancer Cancer cancer development cancers Cell cellular response component conserved COVID-19 Crohn's disease different diseases disease drugs dysregulation embryogenesis Factors glioma homolog Host human body immune dysregulation immune response immune system evasion implication Infection infections Inflammation Inflammation Mediators. Inflammatory Influenza inhibit investigated involved lung carcinoma malignancies mechanism medulloblastoma Mutation Pancreatic cancer pathogen pathogen-mediated pathogenic pathway progression receptor receptor inhibitor Research rheumatoid arthritis SARS-CoV-2 viruses shifting signaling pathway targets Therapeutic approach therapeutic strategy tissue homeostasis transcriptional treat Treatment tumors [DOI] 10.1136/jitc-2021-004397 PMC 바로가기 [Article Type] Editorial
Vulture-Based AdaBoost-Feedforward Neural Frame Work for COVID-19 Prediction and Severity Analysis SystemVulture-Based AdaBoost-Feedforward Neural Frame Work for COVID-19 예측 및 심각도 분석 시스템Article Published on 2022-06-012022-09-11 Journal: Interdisciplinary sciences, computational life sci [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy affected Affected part tracking Analysis chest X-ray Chest X-ray image Chest X-ray images complexity COVID COVID-19 COVID-19 disease COVID-19 severity death deep learning develop disease early stage error rate Feature extraction human body humans identify initial involved machine learning mechanism Neural offer prediction reduce required Research researcher risk Segmentation severity Severity analysis. spread of COVID-19 System virus Vulture work X-ray [DOI] 10.1007/s12539-022-00505-3 PMC 바로가기 [Article Type] Article
Nitric oxide boosters as defensive agents against COVID-19 infection: an opinionCOVID-19 감염에 대한 방어제로서의 산화질소 부스터: 의견Article Published on 2022-06-012022-09-11 Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), SARS, 치료제, [키워드] agent Antiviral compound booster co-morbidity Compound COVID-19 death disease food highest human body immune system Immunity introduced literature nitric oxide NO NO-release pandemic disease Patient Scientific community severity Support symptomatic synthetic moieties. the patient Vaccine viral infection [DOI] 10.1080/07391102.2020.1852969 PMC 바로가기 [Article Type] Article